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Family: Nicolas Ambrosio Lopez Portillo y Soto Maior / Catalina de Balmaceda de la Reatiga (F1444)
m. Abt 1719Miguel Lopéz Portillo (1678- ) 
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Luisa de Sotomayor (1678- )
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| Joseph Lopez Portillo de Soto Maior (1704- ) |
| Maria Luisa Lopez Portillo (1720- ) |
| Juana Josepha Lopez Portillo (1722- ) |
Juan Joseph Lopez Portillo (1724- )  |
| Geronimo Antonio Lopez Portillo (1726- ) |
| Joseph Defonso Lopez Portillo (1729- ) |
| Lorenza Clara Lopez Portillo (1733- ) |
| Joseph Siriaco Lopez Portillo (1733- ) |
| Joseph Francisco Lopez Portillo (1742- ) |